Principal Investigator

Paul Hudson

2009 PhD Chemical Engineering, University of California, Berkeley USA
2004 BSc Chemical Engineering, North Carolina State University USA

In 2013 I helped to start research on cyanobacteria at KTH, on a project to produce butanol. That project evolved into this group. In 2014 I became a SciLifeLab Fellow, and moved to Science for Life Laboratory. As group leader, I direct our ongoing projects so that they complement one another. As an advisor, I want students to learn to look for how research projects fit together. I also want for students to develop technical skills in instrumentation and data processing. It is their success in this that has allowed our research to expand into new areas.

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Elias Englund

2017 PhD Microbial Chemistry, Uppsala University Sweden

I did my PhD in Uppsala University doing metabolic engineering on cyanobacteria for terpenoid production. After that I was a Post-doc researcher at the Joint Bioenergy Institute in Berkeley USA from 2018-2021 working on high throughput polyketide synthase engineering. In the fall of 2021, I joined the Hudson lab. Here I will continue my research interest of applying modern methods for metabolic engineering by developing and applying methods for high throughput engineering of cyanobacteria.

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Ute Hoffmann

2021 PhD Biology, University Freiburg Germany.
2017 MSc Biochemistry & Biophysics, University Freiburg Germany.

During my PhD I tried to unravel the secrets of a central ribonuclease in the cyanobacterium Synechocystis sp. PCC 6803. To do so, I combined both experimental wet lab work and bioinformatic analyses. I am enthusiastic to now use this knowledge to change gear towards more applied research on cyanobacteria and help to investigate the potential use of cyanobacteria and their enzymes to create more sustainable solutions.

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Bruno Rojas

2021 PhD in Biological Sciences, Universidad Nacional del Litoral, Argentina.
2016 MSc in Biotechnology, Universidad Nacional del Litoral, Argentina.

During my PhD, I studied the regulation of enzymes from carbon metabolism in plants using biochemical and biotechnological approaches. Also, during that period I worked in the genetic modification of different plant species to improve agronomic traits. Later, I worked for a company managing biotechnology projects to improve sustainability within the agroindustry. Driven by my passion for sustainability, I joined the Hudson lab to develop my expertise in synthetic biology and to devise strategies to enhance growth and carbon fixation in both plants and cyanobacteria

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Sara Lupacchini

2023 PhD Biology, Helmholtz Centre for Environmental Research, Leipzig.
2018 MSc Cellular and Molecular Biology, University of Turin.

I completed my PhD in the Applied Biocatalysis group at the UFZ in Leipzig, where I focused on engineering cyanobacteria for hydrogen production. Following my doctoral studies, I joined the Hudson Lab as a postdoctoral researcher in autumn 2023. My current research focuses on optimizing CO2 fixation in cyanobacteria and exploiting carbon fixation for bioproduction of target compounds. My work aims to contribute to the development of sustainable solutions for carbon utilization and bio-based production processes.

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Grad Students

Emil Sporre

2020 MSc Medical Biotechnology, KTH Sweden

I joined the group during the Spring of 2020 for my MSc thesis degree project. After graduation, I stayed with the group to keep working on the project – interaction proteomics in autotrophic bacteria. The focus of the project is to explore post-translational regulation of carbon fixation in multiple bacteria to enable a future increase in carbon flux through the cycle. I am also eager and curious to explore other topics, and develop both wet and dry lab skills.

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Anna Karlsson

2021 MSc Industrial Biotechnology, KTH Sweden

I joined the lab in 2021. I am interested in metabolism in all of its varieties. In my master's thesis at KTH I studied the puzzle of amino acid secretion by anaerobic Clostridia. In this group I will work to develop and apply new proteomics methods for cyanobacteria and plant. Our hope is to uncover new types of regulation in carbon fixation. Alteration of these regulations could lead to cells with faster carbon uptake or altered product secretion.

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Axel Knave

2022 MSc Industrial Biotechnology, KTH Sweden

My time in the group started in the beginning of 2022 as a masters student. During the thesis I worked with evaluating cyanobacteria enzyme libraries in vivo. As a PhD student I am now working on synthetic biology of cyanobacteria, where I am to find and produce alterations in central metabolism and carbon uptake cycle. The methods of choice for this are primarily proteomics, metabolomics, and mutagenesis. My hope is to produce a strain with a deregulated carbon uptake, and to also harness this increased uptake towards specific products.

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Michele Russo

2023 MSc Molecular Biotechnology at the University of Pisa.
2021 BSc Biological Sciences at the University of Pisa.

I joined the group in Fall 2023. Here is some additional background about me! From 2018 to 2023 I was a Student in Biological Sciences at the Scuola Normale Superiore, Pisa. I was a participant at the EPFL School of Life Sciences Summer Research Program in 2022, Lausanne. I was part of the Max Planck Summer Internship Program in 2021, in Munich. I also attended the 29th International Biology Olympiad, 2018, Tehran. As a Ph.D. student I am working on different platforms for Adaptive Laboratory Evolution of Photoautotrophs.

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Synechocystis strain PCC 6803

Evolved billions of years ago

I was isolated for research around 1970 from a lake near Berkeley, California. I was the first photosynthetic organism to have a genome sequenced. My main interests are light and CO2. I exist in thousands of tubes and flasks around the world. Through this distributed existence I silently and relentlessly sample genetic mutation. In some of my many permutations, I can consume glucose. In others I move toward the light, in others still I retract from it. I joined this group in 2011, was discarded after a contamination was discovered, but returned again in 2012.

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Graduate students

  • Markus Janasch, Senior researcher, SINTEF Norway
  • Ivana Cengic, Research scientist, Annoca Biotech Sweden
  • Jan Karlsen, Research Scientist, Volta Greentech Sweden
  • Johannes Asplund-Samuelsson, Data Scientist, Scania Sweden
  • Kiyan Shabestary, Postdoc Imperial College UK
  • Josefine Anfelt, Scientist, Cytiva Sweden


  • Rui Miao, Researcher, Uppsala University
  • Nick Crang, National Genomics Infrastructure NGI Stockholm
  • Michael Jahn, Bioinformatician, Max-Planck Institute for Infection Biology
  • Arvid Gynnå, National Forensic Center, Linköping Sweden
  • Lun Yao, Associate Professor, Dailan Institute Chemical Physics
  • Da Wang, Chinese Academy of Sciences
  • Vital Vialas, Data Scientist, Airmee Sweden
  • Danuta Kaczmarzyk, Scientist, Photanol Netherlands
  • Petter Hammar, Scientist, Astrego Therapeutics Sweden
  • Heriberto Velez, Researcher, Sweden Agricultural University

Master's students

  • Anna Schuppe, Ph.D. student KTH Sweden
  • Julia Ramirez, Epigenica Stockholm
  • Gabriel Salemyr
  • Ulysse Castet (MTLS), Research engineer KTH Sweden
  • Axel Knave, Ph.D. student KTH Sweden
  • Weiqi Ding, Research engineer KTH Sweden
  • Amina Bensabra, Consultant at Agap2 Stockholm
  • Linnéa Strandberg, Ph.D. student Université Paris-Saclay
  • Luise Zeckey (MTLS), Ph.D. student LMU Munich
  • Albert Anis, Founder, ValleyDao
  • Cristopher Ollagnier Widen
  • Manuel Bruch, Ph.D. student, University College Dublin
  • Kyle Kimler, Computational scientist, Broad Institute USA
  • Olivia Hallman, Laboratory engineer, GE Healthcare Sweden
  • Emil Ljungqvist, Ph.D. student, KTH Sweden
  • Astrid Nilsson, Research associate, Swedish Environmental Institute
  • Raquel Perucca, Ph.D. student, Lund Sweden
  • Linnea Österberg, Ph.D. student, Chalmers Sweden
  • Quentin Thomas, Ph.D. student, Copenhagen Denmark
  • Susan Bigesse, Process engineer, Rentschler Biopharma Germany
  • Mahanand Muppidi
  • Amanda Särnegrim, Product development, Aerosol Scandinavia

Visiting students and researchers

  • Michelle Verstraaten, Ph.D. student Trondheim
  • Niklas Segerström, Masters student Grenoble
  • Nadia Doge, Ph.D. student University Copenhagen
  • Sara Baldanta, Ph.D. student University Complutense, Madrid
  • Johann Bauerfeind, Founder and CEO, Solaga Germany
  • Dora Vitay, Enginzyme Sweden
  • Josefin van der Meer, Process engineer, Cortus Energy Sweden
  • Anja Erhmann, Ph.D. student, Copenhagen Denmark

Find Us

We are located at Science for Life Laboratory, a “satellite” campus of KTH Royal Institute of Technology.

Visiting address: Tomtebodavägen 23B, 17121 Solna, Sweden. Bus stop “Karolinska Institutet Biomedicum,” Bus lines 3, 6. Nearest subway stop is St. Eriksplan (20 minutes walk).